The American Society for 

Reproductive Immunology

ASRI is excited to announce that with our annual meeting moving to a virtual platform for 2021, we will now be able to include this workshop for all attendees at no additional chargeJust register for the annual meeting, then login on Sunday, May 16 to participate in a special one-day workshop for young investigators on Cutting Edge Technologies in Reproductive Immunology.


The American Society for Reproductive Immunology (ASRI) was founded to foster the field of Reproductive Immunology so both basic researchers and clinicians can better understand the immune-based etiologies underlying reproductive anomalies. Recent revolutionary advances in technical know-how now make it possible to not only investigate the issues in animals but to transport this knowledge from bench to bedside. The objective of the symposium is to provide to new investigators and trainees cutting edge exposure to new techniques for the study of immune cells and organs from the reproductive tract. This workshop will provide "hands on" opportunity and/or technical demonstrations of new technologies with direct application for reproductive immunology to better understand the connections of these technologies to clinical studies and potential clinical application.

Introduction & Overview

10:00 - 10:05

Gil Mor, MD PhD & Charles Wira, PhD

Session 1. Cellular Insights with Live-Cell Imaging

10:05- 10:50

Moderators: Gil Mor, MD PhD & Charles Wira, PhD

Epithelial and immune cell responses to trauma, cell killing, pathogens and antimicrobials

Marta Rodriguez-Garcia, PhD

Sponsor Demonstration - Jocelyn Foye and Chelsea Johnson, SARTORIUS

Live cell imaging is used to demonstrate new approaches for live cell imaging with regular light as well as fluorescence. Live-cell imaging and analysis can provide critical, temporal information about cellular events and downstream effects. You stand to gain a more complete understanding of cellular responses when observing kinetic insights from living, unperturbed cells and combining this with multiomic analysis.

Session 2. High Resolution Ultrasound Imaging

11:00 - 11:45

Moderator: Surendra Sharma, MD, PhD

High resolution ultrasound imaging of the placenta - Irina Burd, MD, PhD, Johns Hopkins University

Sponsor Demonstration - Fred Roberts, FujiFilm/Visual Sonics

High Resolution Ultrasound Imaging. Use in Obstetrics is a safe, noninvasive procedure that uses sound waves to create images of the fetus, placenta and amniotic fluid in animal models and humans. These images can be viewed in real time on a computer monitor by patient and doctor. Of particular importance is the opportunity of providing longitudinal development of the fetus, placenta, and other organs.

Session 3: Single Cell Sequencing

Moderator: David Aronoff, MD

Single Cell RNA Sequencing to Study Early Embryo Development and How this Technique Can be Used to Study Reproductive Immunology Douglas Ruden, PhD, Wayne State University

Sponsor Demonstration - Brian Fitz and Gourab Bhattacharjee, 10x Genomics

Single Cell Sequencing was developed to help advance precision medicine by enabling the accelerated and accessible detection of genomic variability within and across cell populations. Complex diseases evolve, so understanding genetic variability, including transcriptional modifications at the single-cell level, is vitally important for clinical researchers to break the cycle of treatment response, resistance and relapse.

Session 4: Exosomal Isolation and Analysis

2:00 - 2:45

Moderator: Ramkumar Menon, PhD

Role of exosomes in semen on sexual pathogen transmission and immunity - Florian Hladik, MD, PhD, University of Washington

Sponsor Demonstration - ILIAS Biologics

Exosomes and other EVs are present in tissues and can also be found in biological fluids including blood, urine, and cerebrospinal fluid. They are also released in vitro by cultured cells into their growth medium. As the carriers of messages from one cell to another, there cargo includes mRNA, microRNAs and proteins. This are increasingly important under normal and pathological conditions

Session 5: Microbiome Analysis

3:00 - 3:45

Moderator: Indira Mysorekar, PhD

Impact of vaginal microbiome on HIV susceptibility, inflammation, and antiretroviral therapy - Adam Burgener, PhD, Univ. Manitoba

Sponsor Demonstration - Karen Rodland, Qiagen

Microbiome Analysis reveals metabolic functions that are enriched or underrepresented in the human reproductive tract microbiome. Microbiomes are known to vary between mucosal sites and can provide information on ensuing diseases. Understanding the microbiome creates the opportunity for correcting pathological conditions by modifying the immunological environment.

Diversity & Inclusion: Our Foundation for Scientific Innovation

Many of the greatest ideas and discoveries come from a diverse mix of minds, backgrounds and experiences, and we are committed to cultivating an inclusive work environment. ASRI provides equal opportunities to all members and applicants for awards without regard to race, religion, color, age, sex, national origin, sexual orientation, gender identity, genetic disposition, neurodiversity, disability, veteran status or any other protected category under federal, state and local law.

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