ASRI is excited to announce that with our annual meeting moving to a virtual platform for 2021, we will now be able to include this workshop for all attendees at no additional charge! Just register for the annual meeting, then login on Sunday, May 16 to participate in a special one-day workshop for young investigators on Cutting Edge Technologies in Reproductive Immunology.
The American Society for Reproductive Immunology (ASRI) was founded to foster the field of Reproductive Immunology so both basic researchers and clinicians can better understand the immune-based etiologies underlying reproductive anomalies. Recent revolutionary advances in technical know-how now make it possible to not only investigate the issues in animals but to transport this knowledge from bench to bedside. The objective of the symposium is to provide to new investigators and trainees cutting edge exposure to new techniques for the study of immune cells and organs from the reproductive tract. This workshop will provide "hands on" opportunity and/or technical demonstrations of new technologies with direct application for reproductive immunology to better understand the connections of these technologies to clinical studies and potential clinical application.
Epithelial and immune cell responses to trauma, cell killing, pathogens and antimicrobials
Sponsor Demonstration - Jocelyn Foye and Chelsea Johnson, SARTORIUS
Live cell imaging is used to demonstrate new approaches for live cell imaging with regular light as well as fluorescence. Live-cell imaging and analysis can provide critical, temporal information about cellular events and downstream effects. You stand to gain a more complete understanding of cellular responses when observing kinetic insights from living, unperturbed cells and combining this with multiomic analysis.
11:00 - 11:45
Moderator: Surendra Sharma, MD, PhD
High resolution ultrasound imaging of the placenta - Irina Burd, MD, PhD, Johns Hopkins University
Sponsor Demonstration - Fred Roberts, FujiFilm/Visual Sonics
High Resolution Ultrasound Imaging. Use in Obstetrics is a safe, noninvasive procedure that uses sound waves to create images of the fetus, placenta and amniotic fluid in animal models and humans. These images can be viewed in real time on a computer monitor by patient and doctor. Of particular importance is the opportunity of providing longitudinal development of the fetus, placenta, and other organs.
Moderator: David Aronoff, MD
Single Cell RNA Sequencing to Study Early Embryo Development and How this Technique Can be Used to Study Reproductive Immunology - Douglas Ruden, PhD, Wayne State University
Sponsor Demonstration - Brian Fitz and Gourab Bhattacharjee, 10x Genomics
Single Cell Sequencing was developed to help advance precision medicine by enabling the accelerated and accessible detection of genomic variability within and across cell populations. Complex diseases evolve, so understanding genetic variability, including transcriptional modifications at the single-cell level, is vitally important for clinical researchers to break the cycle of treatment response, resistance and relapse.
2:00 - 2:45
Moderator: Ramkumar Menon, PhD
Role of exosomes in semen on sexual pathogen transmission and immunity - Florian Hladik, MD, PhD, University of Washington
Sponsor Demonstration - ILIAS Biologics
Exosomes and other EVs are present in tissues and can also be found in biological fluids including blood, urine, and cerebrospinal fluid. They are also released in vitro by cultured cells into their growth medium. As the carriers of messages from one cell to another, there cargo includes mRNA, microRNAs and proteins. This are increasingly important under normal and pathological conditions
3:00 - 3:45
Moderator: Indira Mysorekar, PhD
Impact of vaginal microbiome on HIV susceptibility, inflammation, and antiretroviral therapy - Adam Burgener, PhD, Univ. Manitoba
Sponsor Demonstration - Karen Rodland, Qiagen
Microbiome Analysis reveals metabolic functions that are enriched or underrepresented in the human reproductive tract microbiome. Microbiomes are known to vary between mucosal sites and can provide information on ensuing diseases. Understanding the microbiome creates the opportunity for correcting pathological conditions by modifying the immunological environment.